Prkdc^m2Btlr

ENU mutagenesis induced a G-to-T transversion at base pair 15,831,282 (GRCm38) on chromosome 16, equivalent to base pair 193,417 in the GenBank genomic region NC_000082. The mutation corresponds to residue 11,142 in the NM_011159 mRNA sequence in exon 78 of 86 total exons. The mutation results in a glycine (G) to premature stop codon (*) substitution at amino acid 3707 (p.G3707*). The effect of the mutation in the mRNA and the encoded protein has not been determined. (J:204502)