在第3内含子上游插入了FRT引导的neo cassette,同时在第3和第8内含子内也插入了loxP位点。随后,通过与b-actin的FLP小鼠品系杂交,删除了选择 cassette。因此,从第4到第8个外显子被loxP位点环绕。(来源:J:204354)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129S4/SvJae)F1
Targeted
插入
--
1
--
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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