在第3内含子上游插入了FRT引导的neo cassette,同时在第3和第8内含子内也插入了loxP位点。随后,通过与b-actin的FLP小鼠品系杂交,删除了选择 cassette。因此,从第4到第8个外显子被loxP位点环绕。(来源:J:204354)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count