一个新霉素抗性基因座替换了8到21号外显子。 Western blot分析证实了心脏、肾脏、胰腺和大脑中没有蛋白质表达(来源:J:201171)
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A neomycin resistance cassette replaced exons 8 through 21. Western blot analysis confirmed the absence of protein expression in the heart, kidney, pancreas and brain. (J:201171)