插入了Velocigene cassette ZEN-Ub1在染色体12(Genome Build37)109,227,679-109,241,350位点间产生了一个13,672bp的缺失,随后通过Cre介导的剔除操作移除了新霉素选择 cassette。(来源:J:136110, J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count