插入了Velocigene cassette ZEN-Ub1导致了染色体4(基因组Build37)45,355,043-45,387,169区间321,27bp的缺失,随后通过Cre介导的剔除移除了诺瓦克林选择标记 cassette。(来源:J:136110, J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count