在Mir181c的上游插入了一个loxP位点。下游则插入了一个FRT-介导的诺卡因抗性基因座,带有3'的loxP位点。通过Flp酶介导的重组,去除了诺卡因抗性元件。随后,通过Cre介导的重组,移除了微小RNA181d。(来源:J:203157)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6N
Targeted
Insertion, Intergenic deletion
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6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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