一个新霉素抗性基因座替换了3到10号外显子。 Western blot分析证实了在小鼠胚胎成纤维细胞、脑、脾、心脏和肺组织中没有蛋白质表达(来源:J:203238)
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A neomycin resistance cassette replaced exons 3 through 10. Western blot analysis confirmed the absence of protein expression in mouse embryonic fibroblasts, brain, spleen, heart and lung. (J:203238)