人类的PIK3CA基因cDNA,其中第1047位的氨基酸由arginine替换为histidine(H1047R),并带有IRE斯-荧光素报告基因,被一个四环素诱导驱动的启动子控制。产生了两条转基因品系,HR-2239和HR-2251。(来源:J:175839)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
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插入
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1
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6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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