人类的PIK3CA基因cDNA,其中第1047位的氨基酸由arginine替换为histidine(H1047R),并带有IRE斯-荧光素报告基因,被一个四环素诱导驱动的启动子控制。产生了两条转基因品系,HR-2239和HR-2251。(来源:J:175839)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count