这段话翻译成中文是: 人类的BRAF基因cDNA,其第1799位由胸腺嘧啶(T)替换为腺嘌呤(A),导致第600位的缬氨酸(V)替换为谷氨酸(Glu,即V600E),并且在N端带有myc标签,由牛甲状腺特异性的促甲状腺素基因启动子控制。定量RT-PCR和Western blot实验确认了甲状腺组织中mRNA和蛋白质的表达。这是表达量较低的那一条。(来源:J:98550)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
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1
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
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Year
IF
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