Cre介导的重组发生在MHPP256h04(13:78,918,316; MM9)和MHPN5k06(13:79,454,030; MM9)这两个MICER克隆之间,目标是恢复功能正常的Hprt基因,并产生一个包含535Mb的大缺失区域,这个区域与大鼠乳腺癌易感性位点Mcs1a的同源区域相同。(来源:J:199158)
Basic Information
Insertion, Intergenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count