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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Pla2g6
tm1Zyao
Alias:
iPLA2beta
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基础信息
表型特征
文献报道
使用含有人工新霉素抗性基因(cassette)的靶向载体,目的是打断exon 2。exon 2包含了起始密码子,通过反转录-聚合酶链反应(PCR)分析肝脏mRNA,来验证该基因是否存在(来源:J:203038)。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
5523997
129S6/SvEvTac
Targeted
插入
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1
10
1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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