ENU诱变产生了导致第107位氨基酸由终止密码子替换为赖氨酸的错义突变(K107X)。 Western blot结果显示E10.5胚胎中没有蛋白表达(来源:196572)
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ENU mutagenesis induced a nonsense mutation that results in the amino acid substitution of a stop codon for lysine at position 107 (K107X). Western blot analysis confirmed the absence of protein expression in E10.5 embryos. (J:196572)