fdtr基因是设计的,带有loxP位点介导的碱性磷酸酶-polyadenylation信号,位于人链霉素抗毒素受体(diphtheria toxin receptor, DTR;他汀结合表皮生长因子样生长因子, HBEGF)的上游,由小鼠钙/钙调素依赖性蛋白激酶IIα(CamKIIalpha)驱动的转录调控。产生了A和B两个品系,其中B品系的表达相较于A品系有所降低。(来源:J:197654)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6NTac
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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