fdtr基因是设计的,带有loxP位点介导的碱性磷酸酶-polyadenylation信号,位于人链霉素抗毒素受体(diphtheria toxin receptor, DTR;他汀结合表皮生长因子样生长因子, HBEGF)的上游,由小鼠钙/钙调素依赖性蛋白激酶IIα(CamKIIalpha)驱动的转录调控。产生了A和B两个品系,其中B品系的表达相较于A品系有所降低。(来源:J:197654)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count