针对Ezh2基因的第8外显子设计了一个短发夹RNA,它被定向插入到特定位置。这种RNA序列受H1/tetO融合驱动的调控元件和由CAGGS启动子驱动的优化的tet重抑制子(itetR)控制。(来源:J:202724)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
Targeted
插入
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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