在第21外显子上游插入了一个loxP位点。下游的exon 22处插入了一个带有3' loxP位点的FRT引导的诺卡因抗性 cassette,通过Flp介导的重组,这个诺卡因抗性 cassette被移除,剩下21和22外显子是可剪接的。(来源:J:199259)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129P2/OlaHsd)F1
Targeted
插入
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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