插入了Velocigene cassette ZEN-Ub1导致了3号染色体(Genome Build37,位置从54,165,068-54,194,322)上29,255个碱基对的缺失,随后通过Cre介导的剔除操作移除了新霉素选择 cassette。(来源:J:136110, J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count