构建了一个靶向载体,用于将带有3'β-珠蛋白poly(A)末端和loxP介导的PGK-诺瓦克林筛选 cassette插入第2外显子,替换整个编码序列。通过Cre介导的重组,去除了诺瓦克林筛选 cassette。(来源:J:101977, J:139151)
Basic Information
129S1/Sv-Oca2+ Tyr+ Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count