染色体16包含一个大约10.0兆碱基的重复,这是通过在ES细胞中通过Cre介导的重组,在Hspa13(之前称为Stch)和App基因上通过Mutagenic Insertion and Chromosome Engineering Resource(MICER)提供的靶向载体进行同源重组后,由loxP座引发的。(来源:J:82809)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129P2/OlaHsd-Hprt1b-m3
Targeted
重复
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--
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4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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