染色体16包含一个大约10.0兆碱基的重复,这是通过在ES细胞中通过Cre介导的重组,在Hspa13(之前称为Stch)和App基因上通过Mutagenic Insertion and Chromosome Engineering Resource(MICER)提供的靶向载体进行同源重组后,由loxP座引发的。(来源:J:82809)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count