核苷酸替换(CC变为AG)导致第342位氨基酸由谷氨酸替换为异亮氨酸(A342E)。通过Flp介导的重组移除了插入在修改后的外显子上游的FRT引导的诺卡因抗性基因座。(来源:198562)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6NTac x 129S6/SvEvTac)F1
Targeted
Insertion, Nucleotide substitutions
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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