Gt(ROSA)26Sor^{tm1(Ptpn22*)Draw}

The construct targeted to the locus contained a floxed STOP cassette, cDNA with the tryptophan for arginine mutation and a N-terminal HA tag, a 2A self-cleaving linker and GFP gene. The mutation is analogous to the human disease-linked variant (LYP-R620W). (J:201448)