小鼠朊蛋白启动子(包含1140bp的朊蛋白基因上游序列、完整exon1、内含子1以及exon2的前52bp),驱动表达全长的人类ATAXIN 3(ATAXIN-3c亚型),该亚型含有148个CAA重复。建立了三线,但仅148.19线产生了后代。(来源:J:122993)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6N
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1
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3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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