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中文
Exon 2被替换为一个修改过的Exon 2，其中C到G的点突变导致第67位的氨基酸由天冬氨酸替换为组氨酸（p.H67D）。这个突变复制了人类Hereditary Hemochromatosis（HH）中许多患者观察到的p.H63D变异。通过Cre介导的重组，去除了内含子2中由loxP序列标记的诺卡因抗性基因元件。（来源：J:201948）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
