在启动子中的一种SNP(非抑制型为T,抑制型为C),在抑制型菌株中会导致顺式增强转录表达。通过比较Clockm1Jt杂合子与C57BL/6、C58/J、BTBR、I/LnJ、MA/MyJ、JF1/Ms、MOLF/EiJ和CZECHII/EiJ的表现,品种A/J、AKR/J、BALBcJ、C3H/HeJ、DBA/2J、FVB/NJ、SJL/J和129S1/SvlmJ被识别出来,它们能够抑制Clockm1Jt基因导致的昼夜节律周期的延长。(来源:J, 198519)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
multiple strains
Not Applicable
单点
--
1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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