ENU mutagenesis induced an A to G transition at base pair 80840778 (v38) on chromosome 4 in the GenBank genomic region NC_000070 encoding Tyrp1. The mutation corresponds to residue 1159 in the mRNA sequence (NM_031202.2) in exon 4 of 8 total exons. The mutation results in a conversion of tyrosine (Y) to cysteine (C) at residue 296. (J:201717)