一个新霉素抗性基因座替换了exon 3到exon 8的部分序列。 Western blot分析证实了肝脏和鼠胚胎成纤维细胞中蛋白表达的缺失。(来源:J:200375)
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A neomycin resistance cassette replaced part of exon 3 through part of exon 8. Western blot analysis confirmed the absence of protein expression in liver and mouse embryonic fibroblasts. (J:200375)