构建了一个包含cre/ERT2(Cre重组酶和雌激素受体1tamoxifen结合域融合基因)的转基因元件,该元件由大鼠Eno2(神经性葡萄糖-6-磷酸酶2)启动子调控,将此转录单元注入了FVB/N雌鼠的受精卵中。随后建立了Founder line 1品系。这些小鼠与C57BL/6、129和ICR背景的混合品系进行了杂交。(来源:J:201038, J:210655)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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