设计了一个靶向载体,包含在第7外显子两侧的loxP位点,同时在第6内含子插入了frt-flanked诺卡因(neo)抗性元件,以及在第7内含子插入了frt-flanked普罗米休斯(puro)抗性元件。(来源:J:227671)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NTac
Targeted
插入
--
1
1
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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