插入了Velocigene cassette ZEN-Ub1导致染色体6(Genome Build37)上5,860,5654-5,864,2427位置之间删除了36,774个碱基对,随后通过Cre介导的去选系统移除了诺瓦克林选择标记 cassette。(来源:J:136110, J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count