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中文
前三个外显子由loxP座和FRT座引导，第三个外显子内插入了由loxP座和抗氨苄青霉素抗性基因座（neomycin resistance cassette）构成的元件。通过基因靶向，这些经过正确编辑的鼠被与Cre表达鼠杂交，以去除1-3号外显子和选择性基因座。删除鼠细胞的蛋白提取物中未检测到蛋白质活性。（来源：195301）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
