在loxP位点、FRT位点、诺卡因抗性基因座、lox2272位点、poly(A)序列和FRT位点,Ptf1a的exon 1和Ptf1aos的exons 1和2被替换。RT-PCR确认了E9.5胚胎中这两个转录本的表达缺失。这个突变是在含有Etn2Sd的ES细胞中产生的。(来源:J:195133)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
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1
4
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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