在第4个内含子中插入了loxP位点,随后是含FRT标记的氨苄青霉素抗性筛选元件,紧接着是第二个loxP位点插入在第7个内含子。通过flp重组酶,这个筛选元件在靶向正确的小鼠中被剔除。(来源:J:194832)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
插入
--
1
--
10

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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