在exon 4之后插入了一个带有5' loxP位点的FRT引导的neomyocin抗性基因座。随后在exon 7下游位置插入了另一个loxP位点。通过Flp介导的重组,去除了neomycin抗性基因座,使得exons 4到7成为可删除的(来源:J:196483)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129S4/SvJae)F1
Targeted
插入
--
1
2
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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