在exon 4之后插入了一个带有5' loxP位点的FRT引导的neomyocin抗性基因座。随后在exon 7下游位置插入了另一个loxP位点。通过Flp介导的重组,去除了neomycin抗性基因座,使得exons 4到7成为可删除的(来源:J:196483)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count