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中文
将编码灵长类表皮生长因子（HB-EGF）/增强型绿色荧光蛋白融合蛋白的序列、Frt-flanked neo/kanamycin抗性元件和polyadenylation信号插入到含有Ucp1启动子的BAC载体中，通过重组技术纯化后，这个BAC构建被注入C57BL/6N的受精卵中，成功建立了Line 445小鼠品系。随后，这些小鼠与Tg(ACTBFLPe)9205Dym小鼠杂交，以剔除抗性元件。(来源：J:198491)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
