将编码cre/ERT2融合蛋白、Frt内含子介导的neo cassette和polyadenylation信号的序列,通过重组修复技术插入到含有Ucp1启动子的BAC中。neo标记未移除,因为原始构建显示了更高效的cre活性。纯化后的构建通过微注射注入了C57BL/6N的成熟卵母细胞中,建立了Line 426。(来源:J:198491)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6N
--
插入
--
--
--
24

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部