所使用的靶向构建包含在内1号 intron中插入的β-geo融合基因的剪接接受器周边的lox重组位点。在未剪接状态下,β-geo融合基因的存在会干扰该基因的表达。当发生重组时,内源基因的剪接和表达可以恢复。(来源:J:196476)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入
--
1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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