这个插入到定位点的靶向构建包含了一个驱动野生型人类cDNA普遍表达的CAG启动子,cDNA前面有一个可删除的STOP cassette,后面跟着一个IRES和部分人类CD2标签。通过Cre介导的重组,去除了这个STOP cassette(来源:J:196002)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
Targeted
插入
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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