在一段2.5千碱基的前导序列中,针对大脑特异性的Slc12a5同源物插入了经过密码子优化并红移的意大利萤火虫(Luciola italica)荧光素酶(redLUC)。在晚期胚胎皮层神经元中,荧光素酶的表达与已知的Slc12a5表达模式相符。(来源:198265)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
--
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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