设计了一种靶向载体,其在exon 2的上游插入了loxP位点,随后是exon 3下游的另一个loxP位点,接着是一个由frt标记的诺卡因抗性(neo)基因座。通过Flp介导的重组,去除了诺卡因抗性基因座。(来源:J:197442)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129S4/SvJae)F1
Targeted
插入
--
1
20
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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