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中文
一个包含内含子(IRES)、Mapt和lacZ融合物(Tau-LacZ)的盒式载体，以及一个被修饰过的neo cassette，替换了第8外显子的原有开放阅读框。这个插入导致了外周区域的错义突变。 Western blot结果显示大脑中没有检测到蛋白表达。(来源：J:196042)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
