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中文
在第4外显子上游和下游插入了LoxP位点，伴随一个由FRT序列包被的诺卡因抗性基因座。随后，这些实验鼠与表达Flp的鼠交配，再让后代与表达Cre的鼠交配，以首先去除选择性基因座，然后删除第4外显子。对鼠脑的定量RT-PCR结果显示mRNA水平下降。免疫学研究证实了脑内没有检测到蛋白质产物。(来源：J:194266)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
