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中文
这个转基因包含了完整的人类主要组织相容性复合体（MHC）II类D区受体（HLA-DPA1*1:03）01:03变异体的全长cDNA，插入到小鼠基因组DNA片段中，该片段位于H2-Aa抗原α（H2-Aa）基因座的启动子下游。人类cDNA后面跟着小鼠的H2-Aa3'非编码序列。携带有这个转基因的杂交瘤鼠（Tg(H2-Ab1-HLA-DPB1)1Lone）表达出特异性的HLA-DPα103/DPβ401复合体，能被抗HLA-DP单克隆抗体B72识别。（来源：J:197820）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
