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中文
Exon 4被通过将TALEN mRNA导入到B6.Cg-Fcgrttm1Dcr背景的Tg(FCGRT)32Dcr/DcrJ卵母细胞中来靶向。这些后代筛选后发现，染色体5上90,464,113位点有一个2个碱基对的缺失，位置在GRCm38.p2。这预测会导致框架移位，随后在编码框架移位下游5个氨基酸处产生一个早停密码子。通过ELISA检测，杂合体的血清albumin水平大约降低了30%，而纯合体的血清albumin则检测不到。(来源：J:220803)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
