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中文
第二外显子被替换为一个经过修改的第二外显子，包含人工启动子甲硫氨酸、FLAG和HA标签，以及导致第26位氨基酸由异亮氨酸变为苯丙氨酸(26I到A)的核苷酸变异。这种突变产生了酶活性受损的E3连接酶蛋白。通过Flp介导的重组，去除了位于修改第二外显子上游的FRT引导的羟氨苄青霉素抗性基因座。(来源：J:177853, J:197744)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
