L1cam^tm2.1Vlem

Nucleotide substitution(s) result(s) in the amino acid substitution of alanine for tyrosine at position 1176 (Y1176A). This allele lacks the AP-2 binding site and a site involved in ERM interactions. Cre-mediated recombination removed the floxed neo cassette inserted into intron 26. Western blot analysis confirmed expression of the protein in the brain. (J:197240)