这个靶向构建引入了一个带有STOP cassette的删除子,后面跟着人源CDT1(30-120位氨基酸)的mCherry融合物以及泛素化区域。通过Cre介导的重组,移除了STOP cassette。这种基于荧光的泛素化细胞周期指示器在细胞周期G1期时会积累在细胞核中。(来源:J:196795)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6NCrlj x CBA/JNCrlj)F1
Targeted
插入
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部