将含有GFP/cre/ERT2(绿色荧光蛋白、Cre重组酶和雌激素受体1tamoxifen结合域融合基因,以及FRT标记的PGK-NEO筛选 cassette)的靶向载体插入Prg4(蛋白聚糖4,巨核细胞刺激因子,关节表皮区蛋白)外显子2的起始密码子位置。生成的嵌合动物与表达FLP重组酶的ACT-FLPe小鼠(未知遗传背景)杂交,以去除FRT标记的PGK-NEO筛选 cassette。(来源:J:197163)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
插入
--
1
1
10

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部