这个研究中,他们用RP23-139P21的BAC构建替换了前83kb,加入了诺卡因抗性基因 cassette,这样只表达Tlr7。产生了6个不同的克隆,这些克隆相对于对照有4到16倍的表达量提升。这个特定的克隆显示4到8倍的表达增益。(来源:J:127600)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
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1
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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