通过Cre介导的重组,去除了neo cassette和3、4号外显子。 Western blot结果显示,大脑和视网膜中没有蛋白表达(来源:196355)
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Cre-mediated recombination removed the neo cassette and exons 3 and 4. Western blot analysis confirmed the absence of protein expression in the brain and retina. (J:196355)