在 intron 4 中插入了 loxP 立场,通过同源重组在 intron 5 处插入了带有 FRT 标记的 pgk-neo 嵌合子和另一个 loxP 立场。同源重组通过重组酶作用去除了 neo 嵌合子和 exon 5。(来源:J:195050)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6
Targeted
插入,基因内删除
--
1
2
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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