RMCE在KH2细胞中插入了一个3' UTR内的元件,元件包含tetO,这是一种驱动Yod1 C末端带有HA标签的基因,通过插入导致了第160位丝氨酸被胱氨酸替换(C160S)。这种改变预计会产生催化失活的产物。(来源:J:194608)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129S4/SvJae)F1
Targeted
插入
--
1
24
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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